The opportunity for critical care research will be available to interested residents in either the basic or clinical realms. The research laboratory at DHMC, which is NIH funded, focuses on the effects of injury on host inflammatory states; it includes investigations into neutrophil priming and cytotoxicity, osmolar regulation of the inflammatory signaling cascade, the function of the cytoskeleton in intracellular signal transduction and responses, the function of mesenteric lymph on the development of post injury MOF, and the effects of blood transfusion on recipient inflammatory states. The Trauma registry and Multiple Organ Failure databases provide a wealth of clinical information to supplement our basic science research. The research lab structure is a collaborative effort with the UCHSC Department of Surgery, and includes surgical faculty, full time investigators, research technicians, and surgical research fellows. In addition to database driven clinical research, residents are encouraged to ask novel questions and investigate them in turn.
Current clinical projects of the DHMC faculty include damage control surgical techniques, enteral feeding, the open abdomen, the effect of blood transfusions, the etiology of MOF, and injury patterns in the pediatric population.
Fellow’s Research Projects to Date:
Cha JY, Kashuk JL, Johnson JL, Moore EE, Cothren CC, Moore JB. “When intensive care becomes acutely surgical.”
Sarin EL, Kashuk JL, Cothren CC, Cha JY, Moore JB, Johnson JL, EE Moore. “Not so FAST: Diagnostic peritoneal lavage remains a valuable adjunct to modern imaging techniques.”
Cha JY, Kashuk JL, Moore EE, Sarin EL, Johnson JL, Moore JB, Cothren CC. “The diverting colostomy for trauma is obsolete.”
Zaw-Mon C, Kashuk JL, Moore EE, Nino T, Haenel JB, Biffl WL, Cothren CC, Johnson JL. "Patterns of community acquired MRSA ventilator associated pneumonia in trauma patients"