Antibiotic-associated Colitis—C difficile
This problem happens in people who use antibiotics. It is also more common in older adults and people staying in care centers.
Other things that may raise the risk are:
- Being very sick or having a weakened immune system
- Using medicines that reduce stomach acid
- Having other digestive problems, such as Crohn disease or ulcerative colitis
- Past surgery on the digestive system
You will be asked about your symptoms and health history. A physical exam will be done.
Tests that may be done are:
- A stool sample to look for signs of infection.
- Blood tests to look for signs of infection
- A colonoscopy to view the inside of the large intestine
- A CT scan to view the large intestine
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Edits to original content made by Denver Health.
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a (Antibiotic-associated Diarrhea, Clostridium difficile-induced Colitis, C diff antibiotic-associated colitis)
Crohn’s and Colitis Foundation of America http://www.ccfa.org
National Institute of Diabetes and Digestive and Kidney Diseases http://www.niddk.nih.gov
Canadian Association of Gastroenterology https://www.cag-acg.org
Canadian Digestive Health Foundation http://www.cdhf.ca
Clostridium difficile infection. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/HAI/organisms/cdiff/Cdiff%5Finfect.html. Accessed September 10, 2020.
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Clostridium difficile (C. diff). Centers for Disease Control and Prevention website. Available at: https://www.cdc.gov/cdiff. Accessed September 10, 2020.
McDonald LC, Gerding DN, et al. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clin Infect Dis 2018 Mar 19;66(7):e1.
Probiotics to prevent antibiotic-associated diarrhea. EBSCO DynaMed website. Available at: https://www.dynamed.com/prevention/probiotics-to-prevent-antibiotic-associated-diarrhea-19 . Accessed September 10, 2020.
3/18/2016 EBSCO DynaMed Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T114378/Clostridium-difficile-infection : Sheitoyan-Pesant C, Abou Chakra CN, et al. Clinical and healthcare burden of multiple recurrences of Clostridium difficile infection. Clin Infect Dis. 2016 Mar 1;62(5):574-580.