Interstitial Nephritis
Overview
SymptomsandDiagnosis
Diagnosis
The doctor will ask about your symptoms and health history. A physical exam and urine tests may point to AIN. You may also have:
- Blood tests—to count blood cells and look for certain proteins that show how the kidneys are working
- Kidney biopsy —confirms diagnosis, but not always needed
- Ultrasound
Treatments
Treatment
AIN care depends on the cause. For example, if medicine you take is harming your kidneys, your doctor will make changes. Care also helps other symptoms such as a rash or fever. AIN care may also involve:
- Antibiotics for bacterial infection
- Corticosteroids to reduce inflammation
- Dialysis —a machine works for your kidneys by filtering your blood
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Edits to original content made by Denver Health.
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RESOURCES
National Institute of Diabetes and Digestive and Kidney Diseases https://www.niddk.nih.gov
National Kidney Foundation https://www.kidney.org
CANADIAN RESOURCES
Health Canada https://www.canada.ca
The Kidney Foundation of Canada https://www.kidney.ca
References
Acute interstitial nephritis. EBSCO DynaMed website. Available at: http://www.dynamed.com/topics/dmp~AN~T115064/Acute-interstitial-nephritis . Updated December 9, 2014. Accessed May 30, 2018.
Kodner CM, Kudrimoti A. Diagnosis and management of acute interstitial nephritis. Am Fam Physician. 2003;67(12):2527-2534.
Plakoglannis R, Nogid A. Acute interstitial nephritis associated with coadministration of vancomycin and ceftriaxone: Case series and review of the literature. Pharmacotherapy. 2007:27(10):1456-1461.
Sierra F, Suzrez M, Rey M, Vela MF. Systematic review: Proton pump inhibitor-associated acute interstitial nephritis. Aliment Pharmaco Ther. 2007:26:545-553.
Tubulointerstitial nephritis. Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/genitourinary-disorders/tubulointerstitial-diseases/tubulointerstitial-nephritis. Updated July 2017. Accessed May 30, 2018.