Nephrotic Syndrome In Adults
Tiny filters in the kidneys remove waste from the blood and makes urine. If they are not working well, wastes and fluids build up in the body.
The most common cause is damage from kidney problems such as:
- Focal segmental glomerulosclerosis
- Membranous nephropathy
- IgA nephropathy
- Minimal change disease
Other causes are problems that harm the kidneys such as:
- Diabetic nephropathy
- Buildup of certain proteins—amyloidosis
- Systemic lupus erythematosus
- Certain infections such as HIV
- Sickle cell disease
- Some cancers
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Edits to original content made by Denver Health.
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National Institute of Diabetes and Digestive and Kidney Diseases https//www.niddk.nih.gov
National Kidney Foundation https://www.kidney.org
Health Canada https://www.canada.ca
The Kidney Foundation of Canada https://www.kidney.ca
Kakar S, Kumar V, Singh R. Latest research progress on acute nephrotic syndrome. J Acute Dis. 2017;6:255-259.
Nephrotic syndrome. National Kidney Foundation website. Available at: https://www.kidney.org/atoz/content/nephrotic. Accessed January 4, 2021.
Nephrotic syndrome in adults. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/nephrotic-syndrome-in-adults. Accessed January 4, 2021.
Nephrotic syndrome in adults. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: https://www.niddk.nih.gov/health-information/kidney-disease/nephrotic-syndrome-adults. Accessed January 4, 2021.
Overview of nephrotic syndrome. Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/genitourinary-disorders/glomerular-disorders/overview-of-nephrotic-syndrome#v1056004. Accessed January 4, 2021.