Sjogren syndrome is a disorder that causes the immune system to destroy the glands that make tears and saliva. There are two types:
- Primary—occurs alone
- Secondary—occurs with other rheumatic conditions such as rheumatoid arthritis , scleroderma , or lupus
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The doctor will ask about your symptoms and health history. A physical exam will be done. You may be referred to a specialist. You may also be referred to a dentist for an exam.
Your eyes may be tested. This can be done with:
- Schirmer test to measure tear production
- Slit-lamp exam
Blood tests will be done to look for antibodies linked to this syndrome.
Images of the salivary gland may be taken. This can be done with:
Salivary gland tissue may need to be tested. This can be done with a biopsy.
There is no cure. The goal of treatment is to manage symptoms. Choices are:
- Medicines to ease:
- Joint and muscle pain
- Lifestyle changes, such as drinking plenty of fluids and exercising regularly
People with severe dry eye may need surgery. A plug may be placed in the tear ducts to stop fluid from draining from the eyes.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Edits to original content made by Denver Health.
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a (Primary Sjogren Syndrome; Secondary Sjogren Syndrome)
American Autoimmune Related Diseases Association, Inc. http://www.aarda.org
Sjogren's Foundation http://www.sjogrens.org
Health Canada https://www.canada.ca
Sjogren syndrome. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/sjogren-syndrome. Accessed March 2, 2021.
Sjogren's syndrome information page. National institute of Neurological Disorders and Stroke website. Available at: https://www.ninds.nih.gov/Disorders/All-Disorders/Sj%C3%B6grens-Syndrome-Information-Page. Accessed March 2, 2021.
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2/22/2017 EBSCO DynaMed Systematic Literature Surveillance https://www.dynamed.com/condition/sjogren-syndrome: Luciano N, Baldini, Tarantini G, et al. Ultrasonography of major salivary glands: a highly specific tool for distinguishing primary Sjögren's syndrome from undifferentiated connective tissue diseases. Rheumatology (Oxford). 2015;54(12):2198-2204.
8/1/2019 EBSCO DynaMed Systematic Literature Surveillance https://www.dynamed.com/condition/sjogren-syndrome: Singh JA, Cleveland JD. The risk of Sjogren's syndrome in the older adults with gout: A medicare claims study. Joint Bone Spine. 2019 Feb 7 [Epub ahead of print].