Leptospirosis is caused by specific bacteria resulting from contact with fresh water, wet or dampened soil, or vegetation that has been soiled by urine from an infected animal.
When contact is made with the contaminated material, the bacteria enter the body through open sores or wounds in the skin, or through mucous membranes. When the bacteria has entered the body, it flows into the bloodstream and throughout the body, causing infection.
The following people are at an increased risk of developing leptospirosis:
- Swimmers in lakes, rivers, and streams
- Workers in flood plains
- Workers in wet agricultural settings
- People who have pets, particularly dogs or livestock
- People who work with the land, including farmers, ranchers, loggers, and rice-field workers
- People who work with animals, including veterinarians
Symptoms typically appear about 10 days after infection and may include one or more of the following:
- Sudden fever, chills, pain, and headache
- Dry cough
- Nausea, vomiting, and diarrhea
- Aching joints
- Sore throat
- Painful bones
- Abdominal pain
- Rigid muscles
- Rash on the skin
- Yellow skin and eyes
- Reduced urine output
- Neck stiffness
To help reduce your chances of getting leptospirosis:
- Reduce contact with soil, vegetation, and water that could possibly be contaminated with infected animal urine, including urine from rodents.
- If working with materials that could potentially be contaminated, wear protective clothing that covers the skin, including waterproof boots or waders.
- If working in an especially high-risk area, talk to your doctor about ways to reduce your risk.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Edits to original content made by Denver Health.
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a (Weil's Disease; Icterohemorrhagic Fever; Swineherd's Disease; Rice-Field Fever; Cane-Cutter Fever; Swamp Fever; Mud Fever; Hemorrhagic Jaundice; Stuttgart Disease; Canicola Fever)
Centers for Disease Control and Prevention http://www.cdc.gov
World Health Organization http://www.who.int
Ellis T, Imrie A, Katz AR, Effler PV. Underrecognition of leptospirosis during a dengue fever outbreak in Hawaii, 2001-2002. Vector Borne Zoonotic Dis. 2008;8(4):541-547.
Hartskeerl RA, Collares-Pereira M, Ellis WA. Emergence, control and re-emerging leptospirosis: dynamics of infection in the changing world. Clin Microbiol Infect. 2011;17(4):494-501.
Katz AR, Buchholz AE, Hinson K, Park SY, Effler PV. Leptospirosis in Hawaii, USA, 1999-2008. Emerg Infect Dis. 2011;17(2):221-226.
Leptospirosis. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/leptospirosis. Updated November 18, 2014. Accessed June 11, 2015.
Leptospirosis. EBSCO DynaMed website. Available at: http://www.dynamed.com/topics/dmp~AN~T116239/Leptospirosis . Updated September 8, 2015. Accessed September 27, 2016..
Leptospirosis (Weil's disease). New York State Department of Health website. Available at: http://www.health.ny.gov/diseases/communicable/leptospirosis/fact%5Fsheet.htm. Updated October 2011. Accessed June 11, 2015.
Stern EJ, Galloway R, Shadomy SV, et al. Outbreak of leptospirosis among Adventure Race participants in Florida, 2005. Clin Infect Dis. 2010;50(6):843-849.