QT Dispersion in Anorexia Nervosa

October 01, 2005

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We read with interest Roche and colleagues’ article1 demonstrating normalization of QT dynamicity and measures of heart rate variability (HRV) with refeeding in anorexia nervosa (AN). We previously observed a more than twofold increase in QT dispersion in patients with chronic anorexia nervosa compared with age-matched controls.2 In addition, our data suggest that patients with AN with a low metabolic rate at rest, at their nadir weight, appear to be at greater risk for increased QT dispersion. Roche and colleagues also noted a lack of QT prolongation among their 10 subjects, which we and other authors2,3 previously demonstrated.

  1. Mehler PS, Krantz MJ. QT Dispersion in Anorexia Nervosa. American Journal of Cardiology 96(7):1034, 2005. (Ltr) | https://www.ajconline.org/article/S0002-9149(05)00552-7/abstract