Hypertrophic Cardiomyopathy Adult
Hypertrophic cardiomyopathy (HCM) is a form of cardiomyopathy. This is a condition in which the heart muscle thickens due to genetic problems with the muscle’s structure. As the muscle thickens, it must work harder to pump blood, which strains the heart muscle. Sometimes, the thickened muscle gets in the way of the blood leaving the heart and causes a blockage. This blockage can cause the nearby heart valve, called the mitral valve, to become leaky. HCM can cause uneven muscle growth which can cause the heart to pump in a disorganized way. Rarely, it can cause abnormal heart rhythms that can even be fatal.
There are two types of hypertrophic cardiomyopathy:
- Hypertrophic obstructive cardiomyopathy (HOCM)—the muscle between the two valves of the heart becomes so enlarged that it obstructs the blood flow in the heart
- Non-obstructive hypertrophic cardiomyopathy—non-obstructive form, the enlarged muscle is not large enough to block blood flow
|Normal Heart and Heart with Hypertrophic Cardiomyopathy|
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Causes of HCM include:
- A gene that causes the abnormal structure of the heart muscle. It can be inherited or can happen from changes in the genes over time.
- A defective gene that controls growth of the heart muscle
In people over age 60, HCM is likely to be caused by or related to high blood pressure.
- Chest pain
- Fainting, particularly during exercise
- Lightheadedness, particularly following exercise
- Rapid heartbeat
- Shortness of breath or difficulty breathing
- General fatigue
- Tiring easily during exercise or activity
- Shortness of breath when lying down
These symptoms can be caused by some of the side effects of the condition, including heart arrhythmias. The blocked or reduced blood flow is usually the cause of symptoms like lightheadedness, fainting, and difficulty breathing.
You will be asked about your symptoms and medical history. A physical exam will be done.
Your bodily fluids may be tested. This can be done with blood tests.
Your body's response to exercise may be tested. This can be done with a stress test.
Images may be taken of your bodily structures. This can be done with:
- Transesophageal echocardiogram
- Chest x-ray
Your heart activity may be monitored. This can be done with a portable ECG.
The diagnosis is only made in people who do not have other causes of cardiomyopathy such as amyloidosis, sarcoidosis, coronary or valvular heart disease.
Many individuals with HCM live a normal, healthy life with few symptoms. However, HCM does increase the risk of sudden death.
Treatment focuses on controlling symptoms and preventing complications. Talk with your doctor about the best treatment plan for you. Treatment may include:
Medications may be used to help maintain proper and regular heart function. These may include:
- Beta-blockers and calcium channel blockers
- Blood thinners
The thickened portion of the heart muscle is cut and removed. This may be needed if you have severely blocked blood flow from the heart.
If the mitral valve is leaking, surgery may also be done to repair or replace the mitral valve.
Alcohol Septal Ablation
Alcohol is injected into the arteries of the thickened portion of the heart. This helps to reduce the blockage in the heart and improve blood flow out of the heart.
Implantable Cardioverter Defibrillators (ICD)
This ICD is implanted if you are at increased risk for sudden death.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Edits to original content made by Denver Health.
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a (Cardiomyopathy, Hypertrophic—Adult; HCM—Adult; Idiopathic Hypertrophic Subaortic Stenosis—Adult; Asymmetric Septal Hypertrophy—Adult; ASH—Adult; HOCM—Adult; Hypertrophic Obstructive Cardiomyopathy—Adult)
American Heart Association http://www.heart.org
Cardiomyopathy Association http://www.cardiomyopathy.org
Canadian Cardiovascular Society http://www.ccs.ca
Heart and Stroke Foundation of Canada http://www.heartandstroke.ca
Cardiomyopathy in adults. American Heart Association website. Available at: http://www.heart.org/HEARTORG/Conditions/More/Cardiomyopathy/Cardiomyopathy%5FUCM%5F444459%5FSubHomePage.jsp. Accessed September 15, 2017.
Explore cardiomyopathy. National Heart, Lung, and Blood Institute website. Available at: https://www.nhlbi.nih.gov/health/health-topics/topics/cm. Updated June 22, 2016. Accessed September 15, 2017.
Hypertrophic cardiomyopathy. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115426/Hypertrophic-cardiomyopathy . Updated May 12, 2017. Accessed September 15, 2017.
What is HCM? St. Luke's Roosevelt Hospital Center website. Available at: http://www.hcmny.org/whatis/index.html. Accessed September 15, 2017.