Many people get EBV during their lifetime. Things that raise the risk that EBV will turn into mono are:
- Getting EBV after age 10
- Lowered immune system due to other illness, stress, or lack of energy
- Living in close quarters with many people, such as in a college dormitory
Getting mono once means a person will be immune to it in the future.
Signs of mono start 4 to 7 weeks after a person was exposed to the virus. The first symptoms may be a sense of weakness that lasts about 1 week. Next, a person may have:
- High fever
- Severe sore throat
- Swollen glands
- Lack of energy
- Loss of hunger
- Muscle aches
- Belly swelling
- Yellowing of the skin and whites of the eyes
There is no way to cure mono or to shorten the length of the illness. It lasts 4 to 6 weeks, but the lack of energy may last longer.
The goal is to manage symptoms. Choices are:
- Lifestyle changes, such as limiting contact sports and heavy lifting to avoid injury to a swollen spleen
- Supportive care, such as getting rest, drinking plenty of fluids, and gargling with salt water
- Medicines to ease pain and swelling in the throat, such as pain relievers or steroids
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Edits to original content made by Denver Health.
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a (Infectious Mononucleosis; Mono)
Centers for Disease Control and Prevention http://www.cdc.gov
National Institute of Allergy and Infectious Diseases http://www.niaid.nih.gov
About Kids Health—The Hospital for Sick Children http://www.aboutkidshealth.ca
The College of Family Physicians of Canada http://www.cfpc.ca
Dunmire SK, Verghese PS, et al. Primary Epstein-Barr virus infection. J Clin Virol. 2018 May;102:84-92.
Ebell MH, Call M, et al. Does this patient have infectious mononucleosis?: The rational clinical examination systematic review. JAMA. 2016 Apr 12;315(14):1502-1509.
Epstein-Barr virus (EBV) infection. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/epstein-barr-virus-ebv-infection . Accessed October 28, 2020.
Mononucleosis. Family Doctor—Academy of Family Physicians website. Available at: http://familydoctor.org/familydoctor/en/diseases-conditions/mononucleosis.html. Accessed October 28, 2020.